Year: 2025
Type: article
Abstract: Nanotherapeutics has transformed cancer treatment by providing drug molecules at the sites of action with reduced systemic toxicity and maximum therapeutic efficacy. This review gives an overview of recent advancements in nanomedicine such as liposomes, polymeric nanoparticles, dendrimers, and metallic nanoparticles that provide targeted tumor targeting by passive and active means. The nanocarriers achieve maximum bioavailability, achieve controlled drug release, and improve patient outcome. Besides, nanotechnology has also been incorporated into biomedical imaging, immunotherapy, and artificial intelligence (AI) to enhance diagnostic accuracy, allow personalized therapies, and maximize drug delivery. Iron oxide and gold nanostructures have also shown promise for MRI contrast agents and photothermal therapy using nanoparticles. Despite tremendous advances, clinical translation, mass production, and regulatory approvals pose challenges. Future research needs to address tumor heterogeneity, nanoparticle stability, and patient-specific tolerance to achieve the full potential of nanomedicine. The convergence of AI, immunotherapy, and nanotechnology has much to revolutionize oncology and enhance the survival of cancer patients..
Source: Journal of Neonatal Surgery
Authors: Pramod Kumar, Shrimohan Shrivastava, Zeeshan Ansari, Ayush Chaurasia, Vishal Chauhan, Pallavi Tiwari
Institution: Chhatrapati Shahu Ji Maharaj University
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4411039110