Supplemental Figure 1 from CAR Binders Affect CAR T-cell Tonic Signaling, Durability, and Sensitivity to Target
Year: 2025
Type: supplementary-materials
Abstract: Supplemental Figure 1: a-b) Primary human T cells stimulated using anti-CD3/28 beads and on the following day were transduced with indicated CARs. Cells were stained with G4S linker antibody (a) and FITC-labeled human CD19 protein (b). c) After 12 days of culture, CAR expression was evaluated using FITC-labeled human CD19 protein.
Authors: Divanshu Shukla, Khatuna Gabunia, Shannon E. McGettigan, Prachi R. Patel, Shannon Christensen, Ting-Jia Fan, Decheng Song, Yanping Luo, Yanling Wang, Huaishan Wang, Regina M. Young, Carl H. June, John Scholler, James L. Riley
Language: English
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4411039249