Year: 2025
Type: article
Study design: Case Report
Abstract: Spinal metastases originating from glioblastoma (GBM) are exceedingly rare and present significant clinical challenges. The physiopathology behind this phenomenon involves tumor spread via cerebrospinal fluid pathways, particularly in cases where the primary brain tumor is located near the ventricular or subarachnoid spaces. Diagnosing spinal metastases from GBM requires multimodal imaging, which is essential for both confirming the diagnosis and guiding treatment. Treatment options remain limited, with a focus on palliative care, as survival rates for patients with spinal involvement are poor. This case report discusses a 61-year-old woman with a history of glioblastoma who developed secondary spinal metastases, outlining the clinical presentation, diagnostic workup, and management challenges associated with these rare and aggressive metastases.
Institution: Centre Hospitalier Universitaire Mohammed VI
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411041574