Work

Host-Derived Geranylgeraniol Shields Intraerythrocytic Stages of Malaria Parasites from Fosmidomycin

Year: 2025

Type: preprint

Source: Research Square

DOI: 10.21203/rs.3.rs-6574048/v1

Authors: Ignasi Verdaguer, Cathy Chen, Maurício Mazzine Filho, Matheus Santos, Gabriela Castro, Lydia Yamaguchi, Sandra de Oliveira, Manoel Peres, Agustín Hernández, Thales Kronenberger, Daniel Bargieri, Claudia Angeli, Dana Hodge, Giuseppe Palmisano, Luis Izquierdo, Luciana Azevedo, Audrey Odom John, Alejandro Katzin, Marcell Crispim

Institutions: Universidade de São Paulo, Children's Hospital of Philadelphia, Instituto de Pesquisas Tecnológicas, Universitätsklinikum Tübingen, Barcelona Institute for Global Health, Universidade Federal de Alfenas

Language: English

Topic: Malaria Research and Control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Francis Crick Institute, Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico, China Scholarship Council, Universidade de São Paulo, National Institutes of Health

Awards: Biosynthesis of isoprenoids in Plasmodium falciparum. Evaluation of possible targets to obtain new anti-malarial drugs., MEP pathway resistance in Plasmodium falciparum, Structure-based microbially targeted prodrugs

OpenAlex ID: W4411044738

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