Work

Tuberous sclerosis complex with classic clinical triad, subependymal giant cell astrocytoma and subependymal nodules: A case report

Year: 2025

Type: article

Abstract: Tuberous sclerosis complex (TSC) is a rare genetic disorder characterized by benign tumors in multiple organs. We present the case of a 16-year-old male with recurrent headaches, seizures, sebaceous adenomas, and developmental delay—features consistent with the classic triad of Tuberous sclerosis complex (TSC). Imaging revealed multiple subependymal nodules, a subependymal giant cell astrocytoma (SEGA), and mild hydrocephalus. The patient underwent successful ventriculoperitoneal shunt (VP shunt) placement, resulting in resolution of symptoms. This case emphasizes the importance of early diagnosis and imaging in guiding the management of TSC.

Source: Surgery Case Reports

DOI: 10.1016/j.sycrs.2025.100130

Authors: Zermina Tanvir, Khitamul Haq, Huzaifa Ali Khan, Waqar Ahmad, Inibehe Ime Okon, Bipin Chaurasia

Institutions: Nishtar Medical College and Hospital, College of Medical Sciences

Language: English

Topic: Tuberous Sclerosis Complex Research

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $1,330