Work

Primary anorectal melanoma: report of two cases

Year: 2025

Type: article

Abstract: Anorectal melanoma is a rare and aggressive neoplasm with a poor prognosis; the overall survival rate at 5 years is around 20%. We report two clinical cases involving patients who experienced pain and bleeding associated with an anorectal mass. Histopathological studies confirmed the diagnosis of melanoma. The first case presented with localized disease characterized by a black, pedunculated lesion with irreducible prolapse managed with wide local excision. In the second case, the patient had a fixed, pink anal lesion accompanied by multiple inguinal and retroperitoneal lymphadenopathies. Due to the metastatic nature of the disease, immunotherapy was administered. Both patients remain alive after 1 year of follow-up.

Source: Journal of Surgical Case Reports

DOI: 10.1093/jscr/rjaf376

Authors: Ever Frank Lopez-Cutipa, Lizbeth Katherine Quintero-Aquino, Cesar Torres-Mattos

Institution: Hospital Base Guillermo Almenara Irigoyen

Language: English

Topic: Cutaneous Melanoma Detection and Management

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,000