Work

An Online Interactive Map of Human Metabolic Pathways and Associated Genetic Disorders as a Tool for the Biochemistry Classroom

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide In a typical undergraduate biochemistry course, two main educational objectives include (1) understanding and applying how genetic mutations can influence protein structure and function, and (2) examining metabolic pathways of biomolecules to study cellular storage and fuel. Many times, these topics can seem disparate to students; therefore, we have developed a free, online resource that integrates known genetic mutations of enzymes important for human metabolism with a visualization of the associated metabolic pathways. The Metabolic Genetic Disorders Explorer can allow students to synthesize their knowledge of these concepts in a variety of ways.

Source: Journal of Chemical Education

DOI: 10.1021/acs.jchemed.4c01279

Authors: Hannah K. Parker, Beth Zizzamia, Julie A. Pollock

Institution: University of Richmond

Language: English

Topic: Genetics, Bioinformatics, and Biomedical Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Quality education

Open Access status: bronze

Funders: University of Richmond, School of Arts and Sciences, University of Richmond