Work

Thyroid Storm Triggered by Partial Hydatidiform Mole: A Rare and Life-Threatening Complication

Year: 2025

Type: article

Abstract: A 26-year-old woman, gravida 1 para 0 at 14 weeks' 1-day gestation, presented with vaginal spotting and systemic symptoms, including palpitations, shortness of breath, heat intolerance, nausea, and vomiting for 2 weeks. Workup revealed maternal tachycardia, severe-range blood pressure, elevated beta human chorionic gonadotropin of 2,442,400 mIU/mL, suppressed thyroid stimulating hormone, and elevated T4, consistent with thyroid storm with possible preeclampsia with severe features. 1 A transvaginal ultrasound suggested a partial molar pregnancy; this was later confirmed by surgical pathology. This case highlights the rare yet serious complications of hydatidiform mole, in particular, a partial molar pregnancy, including thyroid storm and superimposed preeclampsia, emphasizing the importance of management at a tertiary care center with a multidisciplinary team to optimize maternal outcomes. 2 3.

Source: American Journal of Perinatology Reports

DOI: 10.1055/a-2626-9145

Authors: Hailey Cox, Maggie Wong, Jena Preszler, Nikolina Docheva, Nauman Khurshid

Institutions: ProMedica Toledo Hospital, ProMedica, University of Toledo

Language: English

Topic: Gestational Trophoblastic Disease Studies

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,300