Work

Phototriggered LYTAC: Photoactive Bispecific Aptamer Chimera Enhances Targeted Degradation of Membrane Protein through Regulating Cell Autophagy

Year: 2025

Type: article

Source: Journal of the American Chemical Society

DOI: 10.1021/jacs.5c05456

Authors: Rongjun Zhang, Changjie Yang, Xiaobo Gao, Zhenyang He, Ding-Kun Ji, Weihong Tan

Institutions: Shanghai Jiao Tong University, Renji Hospital, State Key Laboratory of Oncogene and Related Genes, Zhejiang University, Chinese Academy of Sciences, Zhejiang Cancer Hospital

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Natural Science Foundation of Shanghai, National Natural Science Foundation of China, Fundamental Research Funds for the Central Universities

Awards: G567019371, G6284163851, G769252474

OpenAlex ID: W4411082309

FWCI: 7.832

Cites: 37

Cited by: 30

Related to: 10