Work

Association of CSF β-Amyloid Biomarker and Imaging Markers in Cerebral Amyloid Angiopathy

Year: 2025

Type: article

Abstract: Cerebral amyloid angiopathy (CAA) is a small vessel disease characterized by β-amyloid deposition in cerebral vessel walls, leading to hemorrhagic and ischemic injuries. The Boston criteria 2.0 guide CAA diagnosis based on clinical and neuroimaging findings. Although imaging-based phenotypes have been well-defined, data on CSF biomarkers remain limited. Integrating CSF and imaging markers may improve understanding of CAA disease patterns. This study evaluates associations between CSF and neuroimaging biomarkers in CAA.

Source: Neurology Open Access

DOI: 10.1212/wn9.0000000000000026

Authors: Raffaella Chieffo, Anna Del Poggio, Marco Vabanesi, Giacomo Giacalone, Miryam Cannizzaro, Beatrice Dell'Acqua, Marco Bacigaluppi, Mario Orrico, Andrea Falini, Nicoletta Anzalone, Massimo Filippi, Luisa Roveri

Institutions: IRCCS Ospedale San Raffaele, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele, Vita-Salute San Raffaele University

Language: English

Topic: Intracerebral and Subarachnoid Hemorrhage Research

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4411086038

FWCI: 2.819

Cites: 40

Cited by: 5

Related to: 10