Work

Diagnostic Pitfalls in Peritoneal Carcinomatosis: A Case of Pseudomyxoma Peritonei

Year: 2025

Type: article

Abstract: Pseudomyxoma peritonei (PMP) is a rare pathological condition posing significant diagnostic and management challenges. This article presents a clinical case of a 58-year-old female who was initially diagnosed with stage III primary peritoneal carcinoma. Following neoadjuvant chemotherapy, a diagnostic re-evaluation was performed with histopathological and immunohistochemical review of biopsy specimens, which led to a revised diagnosis of mucinous carcinoma with features consistent with PMP. The patient subsequently underwent complete cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC). She has remained disease-free for 12 months post-operatively. This case illustrates the crucial role of pathological assessment in guiding treatment for PMP and demonstrates favorable long-term outcomes with aggressive CRS and HIPEC in appropriately selected patients.

Source: Cureus

DOI: 10.7759/cureus.85474

Authors: Maksim Isachanka, Ilya Tarasau, Olga Matylevich, Siarhei Mavrichev, Alena Dalamanava, Dmitry Rovski, Aliaksei Kurchankou, Mariya Galka, Mikalay Kurchankou

Institutions: St. Elizabeth's Medical Center, N.N. Alexandrov National Cancer Centre

Language: English

Topic: Intraperitoneal and Appendiceal Malignancies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4411087542

FWCI:

Cites: 24

Cited by:

Related to: 10