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Nitrous Oxide: No More a Laughing Matter

Year: 2025
Type: article
Study design: Case Report
Abstract: Nitrous oxide (N₂O) is an uncommon cause of subacute combined degeneration (SCD) of the spinal cord, typically observed in district general hospitals, with most affected patients being male. A genetic predisposition may contribute to the development of this myelopathy, particularly due to polymorphisms in the gene responsible for vitamin B12 processing. Our case is distinct in its presentation, involving prolonged exposure over two years, thoracic dorsal column involvement, and rapid, significant recovery within two months.
Source: Cureus
Language: English
Subfield: Surgery
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4411089309
FWCI: 0.892
Cites: 16
Cited by: 1
Related to: 10