Work

Development of sensor based on electrochemical impedance spectroscopy for the detection of Vitamin D3 using molecularly imprinted polymer@MoSe2 nanosheets

Year: 2025

Type: article

Abstract: Vitamin D is a fat-soluble, a secosteroid hormone that is formed when the skin is exposed to sunlight and is essential for the growth and maintenance of healthy bones. It also plays a major role in muscle functioning, cell growth, etc. Vitamin D exits in two forms mainly Vitamin D 3 and Vitamin D 2 both of which can be obtained from diet or through sun exposure. In this work, an electrochemical sensor based on molecular imprinted polymer (MIP) technique has been devised utilizing polydopamine@MoSe 2 nanosheet for the efficient detection of Vitamin D 3 . The characterizations of the fabricated MIP-based sensor are achieved by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and transmission electron microscopy, and cyclic voltammetry. The electrochemical sensing was performed using electrochemical impedance spectroscopy. The linear range for the detection of Vitamin D 3 was 25–200 ng/mL with a LOD of 0.69 ng mL −1 and sensitivity of 133 Ω (ng/mL) −1 cm −2 . Also, the interference studies along with the control studies were performed to establish the validity of the fabricated sensor.

Source: Discover Electrochemistry.

DOI: 10.1007/s44373-025-00035-9

Authors: A. Archana, Sandhya Rani Majhi, Harshulika Singh, Pratima R. Solanki

Institutions: Jawaharlal Nehru University, Central University of Jharkhand

Language: English

Topic: Electrochemical sensors and biosensors

Subfield: Electrical and Electronic Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: diamond

Funders: Department of Biotechnology, Ministry of Science and Technology, India, Indian Council of Medical Research, Ministry of Health and Family Welfare, Advanced Instrumentation Research Facility

Awards: G138665725, G8610695602