Work

Deep learning assisted non-invasive lymph node burden evaluation and CDK4/6i administration in luminal breast cancer

Year: 2025

Type: article

Abstract: ≥ 4) with an AUC of 0.77. LNPN provided a non-invasive method to assess lymph node metastasis and recurrence risk, potentially reducing unnecessary axillary lymph node dissection (ALND), and facilitating decision-making regarding the intervention of CDK4/6i in luminal breast cancer patients.

Source: iScience

DOI: 10.1016/j.isci.2025.112849

Authors: Yuhan Liu, Jinlin Ye, Zecheng He, Mingyue Wang, Changjun Wang, Jie Lang, Yidong Zhou, Wei Zhang

Institutions: Chinese Academy of Medical Sciences & Peking Union Medical College, Peking Union Medical College Hospital, Hebei University of Technology

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240

Funder: National Natural Science Foundation of China

Award: G600000790

OpenAlex ID: W4411111677

FWCI:

Cites: 43

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Related to: 10