Work

Eco-friendly synthesis of selenium nanoparticles using Cuminum cyminum L extract: Evaluating their cytotoxicity, antimicrobial properties, and photocatalytic efficiency

Year: 2025

Type: article

Abstract: In this study, selenium nanoparticles (Se-NPs) were synthesized through a sustainable and eco-friendly method utilizing Cuminum cyminum L. (cumin) extract. The bioactive compounds in the extract act as natural reducing agents and stabilizers. The morphological, optical, and functional attributes of Se-NPs were analyzed with a focus on their photocatalytic applications, cytotoxicity, and antimicrobial activities. UV-Vis, XRD, and TEM analyses confirmed that Se-NPs were mainly amorphous with a spherical shape. The photocatalytic evaluation showed that Se-NPs effectively degraded organic dyes when exposed to UV light, highlighting their potential for environmental purification. The MTT assay evaluated the potential cytotoxicity of Se-NPs toward the cancerous CT26 cells and showed targeted anticancer activity with an IC 50 value of 309.9 µg/mL after 48 h. The agar diffusion approach was used to study the bactericidal effects of Se-NPs against Escherichia coli and Staphylococcus aureus ; the appearance of clear inhibitory zones confirmed the antimicrobial properties of Se-NPs.

Source: Open Ceramics

DOI: 10.1016/j.oceram.2025.100809

Authors: Fatemeh Nazarzadeh, Saied Navabpour, Zahra Sabouri, Majid Darroudi

Institutions: Gorgan University of Agricultural Sciences and Natural Resources, Mashhad University of Medical Sciences

Language: English

Topic: Nanoparticles: synthesis and applications

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDGs: Responsible consumption and production, Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000