Synthesis of ethanol nanoparticle preparations of white oyster mushroom (pleurotus ostreatus) extract using chitosan and the ionic gelation method
Year: 2025
Type: article
Abstract: Indonesia is a country rich in natural resources, many of which have the potential to be used as traditional medicinal ingredients—one example is the White Oyster Mushroom (Pleurotus ostreatus). The White Oyster Mushroom is known for its high nutritional value, popularity among the public, and ease of cultivation. It contains various active compounds with potential antioxidant and anti-inflammatory properties, including vitamin C, ergothioneine, flavonoids, alkaloids, tannins, saponins, and other phenolic compounds. Since ancient times, the use of mushrooms as medicine in the community has been widely reported, and more research is being conducted to see their potential to become standardized herbal medicine or phytopharmacology. The study aims to describe the synthesis of ethanol-based nanoparticle preparations of White Oyster Mushroom extract using chitosan as a stabilizing agent and the ionic gelation method. Based on the results of the Particle Size Analyzer, Potential Zeta, and Transmission Electron Microscope (TEM) tests, the oyster mushroom extract nano-emulsion showed that the preparation successfully qualified for stable status as a nanoparticle with a size of less than 1000 nm and a potential zeta of more than -30 mV.
DOI: 10.14419/r4prtd76
Institution: Bandung Islamic University
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411124833