Work

Fecal microbiota transplantation through colonoscopy for the management of severe refractory irritable bowel syndrome: Preliminary results

Year: 2025

Type: article

Abstract: Recent studies have explored the role of the microbiota in disorders of gut-brain interaction, opening pathways for therapies, such as dietary adjustments, probiotics, and fecal microbiota transplantation (FMT). We present herein a pilot study on 4 patients with severe irritable bowel syndrome (IBS), refractory to conventional treatment, in which FMT through colonoscopy showed improvement in pain, bloating, and stool consistency that was maintained during the 6-month follow-up. To establish the broader clinical application of FMT, more research on its efficacy according to instillation site and patient results is needed.

Source: Revista de Gastroenterología de México (English Edition)

DOI: 10.1016/j.rgmxen.2025.03.001

Authors: C. von Muhlenbrock, P. Núñez, K. Herrera, N. Pacheco, R. Quera

Institutions: Universidad de Los Andes, Chile, Hospital Clínico de la Universidad de Chile, University of Chile, Hospital San Juan de Dios

Language: English

Topic: Gastrointestinal motility and disorders

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,200