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Efficacy of Plasma Exchange in Myasthenia Gravis Following Long COVID in a Resource-Limited Context: A Case Report

Year: 2025

Type: article

Abstract: This case report describes the development of myasthenia gravis (MG) in a 71-year-old male patient with long COVID and outlines the management of an MG exacerbation. The patient exhibited significant symptoms, including fatigue, cognitive impairment, dysphagia and dysarthria. Although transient improvement was observed after treatment with pyridostigmine, the patient's condition later worsened, with marked axial and buccopharyngeal weakness. Symptom relief was finally achieved with plasmapheresis using a low-volume crossflow gravity-driven method. This case highlights the potential long-term impact of COVID-19 on autoimmune disorders such as MG and emphasizes the need for vigilance in managing post-COVID neurological complications.

Source: Brazilian Journal of Case Reports

DOI: 10.52600/2763-583x.bjcr.2025.5.1.bjcr91

Authors: Rosita Bihariesingh-Sanchit, Rakesh Bansie, Rocade Ma, Sharon Veenbergen, Dimitri Adriaan Diavatopoulos, Marien Isaäk de Jonge, Arno Nierich

Institutions: Academic Hospital Paramaribo, Erasmus MC, Radboud University Medical Center, HemoClear BV (Netherlands)

Language: English

Topic: Myasthenia Gravis and Thymoma

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4411137833

FWCI:

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