Kidney Damage in a Post–Hematopoietic Stem Cell Transplantation Patient With Dense Deposit Disease and Thrombotic Microangiopathy–Like Changes
Year: 2025
Type: article
Study design: Case Report
Abstract: Allogeneic hematopoietic stem cell transplantation (HSCT) is effective for treating hematological malignancies by eliminating abnormal clones and re-establishing donor-derived hematopoiesis and immunity. Post-HSCT kidney damage, particularly glomerulonephritis, is rare but significant. Herein, we describe a case of kidney damage six months after HSCT, presenting as dense deposit disease (DDD) with thrombotic microangiopathy (TMA)-like pathological changes. The patient responded well to immunosuppressive therapy (Table 1).
Source: Kidney International Reports
Authors: Lijun Wang, Zhihuang Zheng, Yijue Song, Yu Cai, Liping Wan, Qing Yu, Jinfang Bao, Jun Liu
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,800
Award: G5653131116
OpenAlex ID: W4411146968