Different Carbohydrate Ingestion Patterns Do Not Affect Physiological Responses, Whole‐Body Substrate Oxidation or Gastrointestinal Comfort in Cycling
Year: 2025
Type: article
Study design: Clinical Trial
Abstract: Fuelling during endurance exercise has evolved towards greater amounts of carbohydrates (CHO) ingested per hour, which can prove challenging for athletes. However, the effects of different CHO ingestion patterns during exercise have scarcely been investigated in cycling. 20 recreationally active males cycled for 180 min at lactate threshold on two occasions in a randomised counterbalanced order. Participants consumed 90 g/h of CHO, either as 22.5 g every 15 min or 45 g every 30 min (CHO-15 and CHO-30, respectively). Respiratory gases, blood glucose, lactate, heart rate, RPE and gastrointestinal symptoms were assessed every 15 min. Physiological responses showed no difference between conditions or significant interactions, except for blood glucose which saw a greater increase in CHO-15 during the first 30 min (interaction; p = 0.03). Whole body CHO and fat oxidation were not different between conditions (2.38 ± 0.37 and 2.33 ± 0.39 g/min, p = 0.25 and 0.19 ± 0.07 vs. 0.22 ± 0.08 g/min, p = 0.10 for CHO-15 and CHO-30, respectively). Subjective markers of gastrointestinal symptoms did not differ between conditions (p > 0.05) except for urge to defecate (p = 0.05); however, only 1 participant reported a score > 4 across any symptoms. Ingesting a larger CHO amount at less regular intervals during prolonged cycling had minimal impact on physiological responses to exercise, whole-body substrate oxidation and gut discomfort, allowing athletes to freely select their preferred strategy.
DOI: 10.1002/ejsc.12336
Authors: Robyn Owen Jones, Mariana Vaz DE Oliveria, Bethan Palmer, Danny Maguire, George Butler, Isabel Gothard, Kate Kavanagh, Jose Areta, Jamie Pugh, Julien Louis
Institution: Liverpool John Moores University
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,680
OpenAlex ID: W4411148216