Work

Correlation between albumin levels during the third trimester and the risk of postpartum levator ani muscle rupture

Year: 2025

Type: article

Abstract: Objective To investigate the correlation between albumin levels during the third trimester and the risk of postpartum levator ani muscle rupture. Methods A retrospective analysis of 410 parturients undergoing vaginal delivery at Zhangzhou Hospital Affiliated to Fujian Medical University was conducted. Parturients were classified into low-albumin (<35 g/L) and normal-albumin (≥35 g/L) groups based on their albumin levels during the third trimester. Data on levator ani muscle rupture and various clinical parameters were collected and analyzed using multivariate binary logistic regression. Results The low-albumin group comprised 38.29% of participants and had a significantly higher incidence of levator ani muscle rupture (53.50%) compared to the normal-albumin group (33.20%; P < 0.05). Albumin levels strongly correlated with rupture risk ( r = 0.193, P < 0.001). Multivariate analysis showed low albumin levels were an independent risk factor (OR = 2.286, 95% CI: 1.259–4.152). Other independent risk factors included forceps-assisted delivery, BMI ≥ 24 kg/m², age ≥ 35 years, and second stage of labor duration ≥ 120 min (all P < 0.05). Conclusion Decreased albumin levels are an independent risk factor for postpartum levator ani muscle rupture, suggesting a potential role in increasing the risk of muscle injury.

Source: Open Medicine

DOI: 10.1515/med-2025-1209

Authors: Yueyun Cai, Yuting Cai, Yuanling Hu, Shengkai Lu, Yueqing Lin

Institution: Fujian Medical University

Language: English

Topic: Pelvic floor disorders treatments

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,373