Electrophoretic Co-Deposition of Chitosan and Cu-Doped Bioactive Glass 45S5 Composite Coatings on AISI 316L Stainless Steel Substrate for Biomedical Applications
Year: 2025
Type: article
Abstract: The growing demands for highly functional biomedical implants necessitate introducing innovative and easy-to-apply surface functionalization techniques, especially when it comes to stainless steel substrates. This study investigated the co-deposition of chitosan and Cu-doped bioactive glass on AISI 316L steel surfaces, with the latter providing a matrix in which fine bioactive glass powders are distributed. Cu-doping into the matrix of bioactive glass was conducted to assess its influence on the bioactivity, antibacterial properties, and structural integrity of the coating. The microstructure, mechanical properties, phase composition, and surface roughness of coated specimens were investigated through a scanning electron microscope (SEM), X-ray diffraction analysis (XRD), energy-dispersive X-ray spectroscopy (EDS), inductively coupled plasma (ICP), contact angles, adhesion tensile tests, and laser profilometry analyses. Results of adhesion tests indicated that Cu addition did not have a major implication for the mechanical properties of the coating layers. Results also revealed that the Cu-doped bioactive glass featured a hydrophilic and a rather uneven surface, both being upsides for biomedical properties. The cytotoxicity and antibacterial assessments showed promising cell viability and antibacterial properties of the deposited coatings.
Source: Crystals
Institution: Isfahan University of Technology
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,534
OpenAlex ID: W4411154899