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Drug-induced systemic lupus erythematosus

Year: 2025

Type: article

Abstract: This case report describes a 63-year-old female patient with hypertension who developed drug-induced systemic lupus erythematosus (SLE) after hospitalization for syncope and severe hyponatraemia. Her complex medication regimen, including antihypertensives and proton pump-inhibitors, complicated the identification of a specific trigger. Positive anti-histone antibodies supported the diagnosis. Treatment with immunosuppressants and discontinuation of suspected drugs led to remission. This case highlights the importance of recognizing drug triggers in elderly patients with extensive medication use.

Source: Ugeskrift for Læger

DOI: 10.61409/v10240784

Authors: Sofie Døssing, Tanja Todberg, Søren Jacobsen, Henrik Christian Bidstrup Leffers

Institutions: Copenhagen University Hospital, Rigshospitalet, Zealand University Hospital

Language: English

Topic: Systemic Lupus Erythematosus Research

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4411185515