Work

Metformin Alleviates Liver Metabolic Dysfunction in Polycystic Ovary Syndrome by Activating the Ethe1/Keap1/PINK1 Pathway

Year: 2025

Type: article

Abstract: Our findings highlight the role and mechanism of metformin in ameliorating abnormal mitophagy and lipid metabolic disorders in the PCOS mice livers and the potential of metformin for addressing NAFLD in PCOS mice.

Source: International Journal of Biological Sciences

DOI: 10.7150/ijbs.104778

Authors: Yuan Xie, Ying Tian, Junting Huang, Wanying Deng, Xiaohui Li, Yujia Liu, Hao Liu, Lei Gao, Qiu Xie, Qi Yu

Institutions: Chinese Academy of Medical Sciences & Peking Union Medical College, Peking Union Medical College Hospital, Sheng Jing Hospital, China Medical University, Harbin Medical University, Chinese Academy of Sciences, Institute of Biophysics

Language: English

Topic: Ovarian function and disorders

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,337

OpenAlex ID: W4411195701

FWCI: 8.401

Cites: 63

Cited by: 12

Related to: 10