Work

Hydroxyl derivatives of 5-CQA and their complexes with water

Year: 2025

Type: article

Abstract: Although the addition of water without a catalyst to α,β-unsaturated carbonyl compounds is unlikely, the results presented in this paper show that this is not necessarily the case with. 5-CQA. The obtained results demonstrate that 5-CQA forms two diastereomeric hydroxyl derivatives, 5-CQA-OH-1 and 5-CQA-OH-2, which are products of water addition to the. 5-CQA molecule via Michael addition. Each of the hydroxyl derivatives of 5-CQA slowly isomerizes and decomposes in aqueous solution. However, after the evaporation of water from their aqueous solutions, they exist in the form of two hydrates, each consisting of two. 5-CQA-OH molecules and two H 2 O molecules.

Source: Journal of Molecular Liquids

DOI: 10.1016/j.molliq.2025.127958

Authors: Piotr Hołowiński, Rafał Typek, Andrzej L. Dawidowicz

Institution: Maria Curie-Skłodowska University

Language: English

Topic: Chemical Reaction Mechanisms

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,480

Funders: Narodowe Centrum Badań i Rozwoju, European Regional Development Fund