Work

Ecstasy as a Potential Cause for Diffuse ST Elevation in a 27-Year-Old Healthy Male: A Case Report

Year: 2025

Type: article

Abstract: Ecstasy, also known as 3,4-methylenedioxymethamphetamine (MDMA), is widely used as a recreational drug known for its stimulating effects. While acute coronary syndrome and coronary vasospasm are frequently observed following cocaine and methamphetamine use, there have been few reported cases linking them to ecstasy use. We present a case of a 27-year-old, previously healthy, male presenting with oppressive retrosternal chest pain and diffuse ST-segment elevation, despite a normal troponin, several days after ecstasy use. His presentation followed by a normal coronary angiography is most consistent with an episode of coronary vasospasm. It is plausible that the consumption of MDMA contributed to this presentation. MDMA can lead to cardiovascular issues by increasing serotonin, dopamine, and noradrenaline levels, which may cause symptoms like coronary vasospasm. Although conclusive evidence linking MDMA to acute coronary syndrome is limited, cases of transient coronary vasospasm and thrombosis have been reported, suggesting a need for prompt evaluation and management of such conditions.

Source: Cureus

DOI: 10.7759/cureus.85795

Authors: Rabih Nasrallah, Amin Ossaily, Mazen Al Hammoud, Anwar Nader, Georges Ghanem

Institution: Lebanese American University

Language: English

Topic: Acute Myocardial Infarction Research

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4411200910