Year: 2025
Type: article
Abstract: Triphenylene derivatives 3PY (2,3,6,7,10,11-hexa(pyridine-3-yl)triphenylene) and 4PY (2,3,6,7,10,11-hexa(pyridine-4-yl)triphenylene) are synthesized using a Suzuki-Miyaura coupling protocol and evaluated as potent chemosensors for the detection of diclofenac in solution phase. Screening against various commonly used nonsteroidal antiinflammatory drugs and hormones demonstrates that the derivatives are selective for diclofenac. The fluorescence quenching mechanism is attributed to the inner filter effect because of the overlap between the UV-vis absorption spectrum of diclofenac and the excitation spectra of triphenylene derivatives. They can sense diclofenac with a low limit of detection of 1.18 μM, offering a simple and cost-effective method. Moreover, the practicability and applicability of the proposed sensor are confirmed in the lake water with reliable recovery and precision.
Source: ChemPlusChem
Authors: Navdeep Kajal, Amar Raj, Rajendhraprasad Tatikonda, Jan Lundell, Matti Haukka
Institution: University of Jyväskylä
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $4,030
Funders: Academy of Finland, Jyväskylän Yliopisto
OpenAlex ID: W4411201430