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Diagnosing Hypoglycemia–from Liver Cancer to Insulinoma: A Case Report

Year: 2025
Type: article
Study design: Case Report
Abstract: Insulinoma is a neuroendocrine tumor originating in the pancreas that secretes excess amounts of insulin, leading to severe hypoglycemia. The clinical presentation of hypoglycemia is classically described by Whipple’s Triad. Due to the rarity of this diagnosis, it can often be mistaken for other etiologies with similar presentations. In this paper, we present the case of a woman in her 70s with metastatic insulinoma involving the liver, who was initially diagnosed with an insulin-like growth factor 2-secreting hepatocellular carcinoma. Biochemical and immunohistochemical analyses were instrumental in distinguishing between these two etiologies.
Language: English
Subfield: Epidemiology
Field: Medicine
Open Access status: hybrid
OpenAlex ID: W4411206950
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