Impact of fiberoptic bronchoscopy with bronchoalveolar lavage on infection control in patients with severe ventilator-associated pneumonia
Year: 2025
Type: article
Study design: Observational Study
Abstract: OBJECTIVES: To evaluate the impact of Fiberoptic Bronchoscopy (FOB) with Bronchoalveolar Lavage (BAL) on infection control in patients with severe Ventilator-Associated Pneumonia (VAP) and compare it with conventional treatments to provide a reliable basis for clinical therapy. METHOD: This retrospective study included 86 patients with severe VAP who were admitted to the hospital between November 2019 and June 2023. Based on the treatment regimen, the patients were divided into two groups: a control group (conventional lavage and suction therapy, n = 32) and an observation group (FOB with BAL, n = 54). RESULTS: ), and pulmonary function indicators (PEF, PEEPi) compared to the control group (p < 0.05). The levels of inflammatory markers in the observation group were notably reduced (p < 0.05). Additionally, the duration of mechanical ventilation, infection control, and length of stay were significantly shorter in the observation group (p < 0.05). There was no significant difference in the incidence of complications between the two groups (p > 0.05). CONCLUSIONS: FOB with BAL as adjunctive therapy for VAP demonstrated significant advantages in enhancing respiratory mechanics, pulmonary function, blood gas analysis, inflammatory response, and bacterial clearance rate while effectively reducing mechanical ventilation duration and length of stay.
Source: Clinics
Authors: Chunfeng Sheng, Xun Xu, Xiaobo Song, Bangfeng Zhao, Yu Zhang, Fengli Si
Language: English
Topic: Nosocomial Infections in ICU
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,700
OpenAlex ID: W4411207354