Management of Severe Hypertriglyceridemia in Pregnancy: Case Report and Therapeutic Strategies
Year: 2025
Type: article
Study design: Case Report
Abstract: Severe hypertriglyceridemia (HTG) during pregnancy is a rare but serious complication, especially in patients with pre-existing dyslipidemia. This condition carries a high risk of acute pancreatitis, obstetric complications, and increased maternal-fetal morbidity. We report the case of a pregnant woman with familial hypertriglyceridemia who developed acute pancreatitis during pregnancy, requiring multidisciplinary management. The therapeutic approach included strict dietary modification, high-dose omega-3 supplementation, and plasmapheresis, which led to a rapid reduction in triglyceride levels and clinical improvement. This case highlights the importance of close monitoring and early intervention in at-risk patients to prevent severe maternal and fetal complications. Personalized management combining dietary measures, appropriate pharmacological therapy, and extracorporeal techniques remains the cornerstone of treatment for severe HTG during pregnancy.
Authors: Oussama Jaddi, Eleazar Niyogushima, Sana Rafi, Sara Ijdda, Ghizlane El Mghari, Nawal EL Ansari
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4411215060