Work

Comparison of Succinylcholine, Rocuronium, and Rocuronium with Magnesium on Time of Onset of Paralysis in Adult Patients Undergoing Rapid Sequence Induction: A Double Blinded Randomised Control Trial

Year: 2025

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: Objective: ) in rapid sequence induction to see if this combination had an onset of paralysis comparable to succinylcholine. Methods: (Group MgR). The primary outcome was the time of onset of paralysis evidenced by fading of train-of-four (TOF). Secondary outcomes were the intubation conditions, and the laryngoscopy response. Results: < 0.001), favouring Group MgR for excellent intubating conditions. Conclusion: The onset of action was significantly faster with succinylcholine than with magnesium sulphate-rocuronium. Nevertheless, it was significantly faster with magnesium sulphate-rocuronium than with rocuronium alone. However, the intubation conditions were better when magnesium was added to rocuronium.

Source: Türk anesteziyoloji ve reanimasyon derneği dergisi

DOI: 10.4274/tjar.2025.251886

Authors: George Paul, Shagufta Naaz, Umesh Kumar Bhadani, Nishant Sahay, Rajnish Kumar, Satish Kumar

Institutions: St. John's National Academy of Health Sciences, All India Institute of Medical Sciences, Patna

Language: English

Topic: Anesthesia and Sedative Agents

Subfield: Anesthesiology and Pain Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4411221175