Work

Rapidly progressive pulmonary abscess initially misdiagnosed as lung cancer: the role of Peptostreptococcus stomatis and Parvimonas micra

Year: 2025

Type: article

Abstract: Pulmonary abscess is a serious infectious disease characterized by localized lung tissue necrosis, primarily caused by anaerobic or facultative anaerobic bacterial infections. While the Streptococcus anginosus group (SAG) is a well-established pathogen in pulmonary abscess formation, recent findings suggest that strict anaerobes such as Peptostreptococcus stomatis and Parvimonas micra can also contribute to deep-seated infections. However, their role in rapidly progressive pulmonary abscesses has not been previously documented. Here, we present a case of a rapidly progressive pulmonary abscess caused by Peptostreptococcus stomatis and Parvimonas micra in an immunocompetent patient, initially misdiagnosed as lung cancer. This case highlights the importance of differentiating infectious lung lesions from malignancies and underscores the clinical utility of metagenomic next-generation sequencing (mNGS) in diagnosing rare anaerobic infections, offering valuable insights for precise diagnostic and therapeutic strategies.

Source: Frontiers in Cellular and Infection Microbiology

DOI: 10.3389/fcimb.2025.1590220

Authors: Hang Hu, Kui Li, Zhidong Jin, Kaijin Wang, Bicui Liu

Institution: Chongqing Medical University

Language: English

Topic: Pleural and Pulmonary Diseases

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801