Work

Structural basis of RNA-guided transcription by a dCas12f–σE–RNAP complex

Year: 2026

Type: article

Source: Nature

DOI: 10.1038/s41586-026-10178-3

Authors: Renjian Xiao, Florian T. Hoffmann, Dan Xie, Tanner Wiegand, Adriana I. Palmieri, Samuel H. Sternberg, Leifu Chang

Institutions: Purdue University West Lafayette, Stanford Medicine, Columbia University, Stanford University, Howard Hughes Medical Institute, Purdue University Institute for Cancer Research

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Awards: Acquisition of Trapped Ion Mobility Spectrometry Time of Flight Mass Spectrometer, Molecular basis for CRISPR RNA-guided nucleic acid cleavage and DNA transposition, Molecular basis for CRISPR-associated transposons and RNA-guided transcriptional regulation

OpenAlex ID: W7133524991

FWCI: 14.21

Cites: 103

Cited by: 7

Related to: 10