Work

Mechanically driven stainless steel-initiated activation of S–H bonds to construct disulfides

Year: 2025

Type: article

Abstract: stainless steel-induced S-H activation. Stainless steel nanoparticles (SS NPs) generated during ball milling facilitated efficient oxidative coupling of thiols under ambient conditions, achieving 41-99.9% yields within 30-90 minutes. The mechanistic studies confirmed the synergistic radical-mediated pathway dominated by iron species, effectively suppressing over-oxidation. This green approach eliminated environmental burdens while offering broad substrate tolerance, advancing sustainable disulfide synthesis for pharmaceutical and material applications.

Source: RSC Advances

DOI: 10.1039/d5ra01836f

Authors: Xujuan Huang, Shiming Zhang

Institution: Zunyi Medical University

Language: English

Topic: Sulfur-Based Synthesis Techniques

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Responsible consumption and production

Open Access status: gold

Estimated APC paid: $1,042