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Novel LPIN2 mutations in Majeed syndrome induce NF‐κB pathway activation

Year: 2025

Type: article

Abstract: This study identifies novel LPIN2 mutations in Majeed syndrome that induce NF-κB pathway activation, linking defective LPIN2 function to aberrant inflammation in this rare autoinflammatory disorder.

Source: Rheumatology & autoimmunity

DOI: 10.1002/rai2.70012

Authors: Yibing Han, Renmei Cai, Yuanxuan Ma, Shiguo Liu, Bin Liu

Institutions: Affiliated Hospital of Qingdao University, Qingdao Municipal Hospital

Language: English

Topic: Inflammasome and immune disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,000

Funder: National Natural Science Foundation of China

Award: G488206240

OpenAlex ID: W4411256539

FWCI:

Cites: 5

Cited by:

Related to: 10