Work

Phase angle as a prognostic factor for postoperative outcomes in major abdominal surgery: a single-center prospective observational study

Year: 2025

Type: article

Abstract: Purpose Phase angle (PA), derived from bioelectrical impedance-analysis (BIA) has emerged as a reliable marker predicting clinical outcomes. This prospective observational study investigated the association between PA and a composite in-hospital outcome in major abdominal surgery. Methods Each patient underwent BIA before surgery (PApre), immediately postoperatively (PApost), and 1 day postoperatively (PAPOD1). Specific assessment for frailty and nutrition status was performed before surgery. Patient outcomes were assessed using a composite adverse outcome comprising death, myocardial infarction, revascularization, stroke, hemodynamic instability, acute kidney injury, pulmonary complications, delirium, ileus, and surgical complications during hospitalization. One-year complication, including all-cause mortality, myocardial infarction, stroke, surgical complications, and readmission after discharge within the year were also assessed. Results A total of 122 adults who underwent major abdominal surgery were enrolled from July 2019 and April 2021. Twenty-three patients (53.5%) in the lower PA group (PA < 5) experienced in-hospital complications compared to 38 patients (34.2%) in the higher PA group (PA ≥ 5) (relative risk, 1.6; 95% confidence interval [CI], 1.0 to 2.4; p = 0.038). PApre was significantly associated with in-hospital complications (odds ratio, 0.491; 95% CI, 0.279 to 0.862; p < 0.001). Patients with lower PApre had a higher degree of frailty, and poor nutritional status. However, PApre was not significantly associated with 1-year composite complications. Conclusion Low PApre was associated with adverse postoperative outcomes after major abdominal surgery. PA can be a reliable prognostic factor to predict in-hospital complications in patients undergoing major abdominal surgery, serving as an alternative surrogate to frailty indices and nutritional markers. Trial registration: Clinical Research Information Services of the Republic of Korea (CRIS identifier: KCT0004160).

Source: Journal of Anesthesia

DOI: 10.1007/s00540-025-03526-6

Authors: Yu Jeong Bang, Dawoon Jeong, Ji Hye Kwon, Yang Jin Park, Jeong‑Jin Min

Institutions: Samsung Medical Center, Sungkyunkwan University, CHA University, CHA University Ilsan Medical Center

Language: English

Topic: Body Composition Measurement Techniques

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,090