Abstract 2483 The Mitochondrial Antiviral Signaling (MAVS) Protein Regulates Vascular Immune Signaling and Metabolism During Systemic Inflammation
Year: 2025
Type: conference-abstract
Abstract: Background: Excessive inflammation can severely damage the lung vascular endothelium, leading to life-threatening conditions such as acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). Key pathogenic mechanisms involve widespread inflammatory activation, increased endothelial cell (EC) permeability, and the formation of lung edema. Gaining insight into the molecular mediators driving inflammation and endothelial barrier disruption could pave the way for innovative treatments targeting vascular injury.
Source: Journal of Biological Chemistry
Institution: University of Illinois Chicago
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,430
OpenAlex ID: W4411273086