Work

Ex vivo spectroscopic characterisation of the biological activity of pancreatic cyst fluid

Year: 2025

Type: article

Abstract: investigation, the first of its kind in this field, a focus was brought to developing a cell line-based model with vibrational spectroscopy for discriminating the response of PDAC cell lines to exposure to PCF. We demonstrate that this approach provides a robust assay which may have potential, with further development, to provide models which are predictive of the trajectory of disease progression in precision medicine.

Source: The Analyst

DOI: 10.1039/d5an00230c

Authors: Outmane Bouzerda, Laura E. Kane, Gregory S. Mellotte, Barbara M. Ryan, Stephen G. Maher, Olivier Piot, Aidan D. Meade

Institutions: Technological University Dublin, BioSpectroscopie Translationnelle, Université de Reims Champagne-Ardenne, Trinity College Dublin, Tallaght University Hospital

Language: English

Topic: Spectroscopy Techniques in Biomedical and Chemical Research

Subfield: Biophysics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Agence Nationale de la Recherche, Technological University Dublin, ADAPT - Centre for Digital Content Technology

Awards: Graduate School in Nano-optics and Nanophotonics, G3251807

OpenAlex ID: W4411274699

FWCI: 0.745

Cites: 36

Cited by: 2

Related to: 10