Year: 2025
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: Study on the effect of targeted drugs on lower urinary tract symptoms (LUTS) in elderly men. METHODS AND MATERIALS: A retrospective study was conducted on elderly male patients aged 60 and above with pathologically diagnosed renal cell carcinoma who received targeted drug therapy. Analyze the prostate volume, international prostate symptom score (IPSS), physical fitness score, and other indicators of these patients before and after receiving targeted therapy. So as to study the effect of targeted drugs on LUTS. RESULTS: A total of 47 patients were surveyed, with an average age of 70.32 ± 7.724 years, and age was significantly correlated with worsening of LUTS. The medication duration is 2-49 months; The average duration of medication was 13.72 ± 9.611 months. With the prolongation of targeted drug treatment time, the occurrence and aggravation of LUTS significantly increase.he logistic regression analysis results indicate that age and duration of medication are both risk factors for the deterioration of LUTS. CONCLUSIONS: It should be cause for concern that use of anti-vascular targeting drugs in elderly men may promote the side effects of LUTS.
Source: The Aging Male
Authors: Li Xiaona, Ren Hailin
Language: English
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,557
OpenAlex ID: W4411277480