Work

Vision Loss as a Rising Global Health Challenge: Comprehensive Analysis of High Fasting Plasma Glucose Burden and Projections to 2035

Year: 2025

Type: article

Abstract: BACKGROUND: Vision loss caused by high fasting plasma glucose (HFG) is a growing global health concern. This study evaluates the global and regional burden of HFG-attributable vision loss from 1990 to 2021 and projects future trends through 2035. METHODS: Using Global Burden of Disease (GBD) 2021 data, we assessed disability-adjusted life years (DALYs) across 204 countries, stratified by gender, age, and Sociodemographic Index (SDI). Temporal trends were analysed using Joinpoint regression, and projections were made using ARIMA modelling. RESULTS: Global DALYs due to HFG-related vision loss rose from 613,694 in 1990 to 1,674,401 in 2021. South Asia and Sub-Saharan Africa experienced the highest burdens, especially among females and older adults. Although age-standardized DALY rates slightly declined globally, they remained elevated in low-SDI regions. Projections suggest a continued increase through 2035. CONCLUSIONS: The burden of vision loss due to HFG is rising, with stark regional and demographic disparities. Urgent, targeted interventions are needed to reduce this growing health burden, particularly in low-SDI areas and among high-risk populations.

Source: Diabetes/Metabolism Research and Reviews

DOI: 10.1002/dmrr.70054

Authors: Zhirui Zhang, Changxing Liu, Xufang Tan, Jiadi Wang, Jing Yao

Institutions: Heilongjiang University of Chinese Medicine, First Affiliated Hospital of Heilongjiang University of Chinese Medicine

Language: English

Topic: Retinal Diseases and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: Harbin Medical University