Work

Primary Squamous Cell Carcinoma of the Uterus and Not the Cervix—A Case Report and Literature Review

Year: 2025

Type: article

Abstract: Primary endometrial squamous cell carcinoma (PESCC) is a rare pathology. Data regarding diagnosis and treatment is limited and is solely based on case reports and series. We report a unique case of a postmenopausal woman with a history of HIV and anal cancer s/p radiation therapy 8 years prior. The patient's presenting diagnosis was malodorous vaginal discharge refractory to antibiotics. The patient had a significant delay in diagnosis since the onset of symptoms despite extensive workup but eventually underwent surgical staging by gynecologic oncology with a diagnosis of Stage IB PESCC. Despite her reported history of anal cancer for which she received an incomplete course of pelvic radiation, the case was discussed at tumor board and the patient was deemed a candidate for external beam radiation therapy. In our report, we discuss, in detail, the patient's presentation, course, and treatment and review the literature.

Source: Case Reports in Obstetrics and Gynecology

DOI: 10.1155/crog/7140494

Authors: Judy Hayek, Mariem Del Rio, Yongmei Yin, Margaux J. Kanis

Institutions: Maimonides Medical Center, NewYork–Presbyterian Brooklyn Methodist Hospital

Language: English

Topic: Endometrial and Cervical Cancer Treatments

Subfield: Obstetrics and Gynecology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $790