Associations between 24-hour movement compositions and cardiometabolic health in children and adolescents: a five-part compositional analysis using data from the International Children’s Accelerometery Database (ICAD)
Year: 2025
Type: article
Abstract: Objectives: The benefits of physical activity (PA) and the negative impacts of sedentary time (SED) on health in youth are well established. However, uncertainty remains surrounding how PA and SED jointly influence cardiometabolic risk (CMR) factors. The aim of this study was to determine the joint influence of SED, light-, moderate- and vigorous-intensity PA (LPA, MPA and VPA), and sleep on CMR factors using five-part compositional analyses. Methods: Data were pooled from 16 cohort studies comprising 22 474 children and adolescents from the International Children's Accelerometery Database. PA was measured using hip-mounted accelerometers with sleep self-reported. CMRs included body mass index (BMI), waist circumference (WC), systolic and diastolic blood pressure, fasting high- and low-density lipoprotein cholesterol, triglycerides, insulin and glucose. Time spent for sleep, SED, LPA, MPA and VPA was analysed using a compositional linear regression model. Results: The overall PA composition explained between 3.0 and 27.0% of the variance in CMR factors after accounting for age, sex, ethnicity and seasonal variation. However, when movement behaviours were explored in isolation, only sleep was associated with all CMR factors. In girls, compositions with 10 min more VPA were associated with a 2.5-4.4% greater BMI and WC. However, 10 min reallocations of time in boys had no impact on any CMR factor. Conclusion: These findings highlight that sleep and VPA are significantly associated with all CMR factors in youth, and therefore specific recommendations are needed to improve the current, and future, health of children and adolescents.
Institutions: Manchester Metropolitan University, Intelligent Health (United Kingdom), University of Illinois Urbana-Champaign, University of Bristol, Northwestern University, University of South Carolina, Centre Hospitalier Universitaire Vaudois, University of Lausanne, University of Strathclyde, University of Lisbon, Centro Interdisciplinar de Estudo da Performance Humana, University of Southern Denmark, University of Cambridge, MRC Epidemiology Unit
Language: English
Topic: Physical Activity and Health
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,839
Funders: Wellcome Trust, Cancer Research UK, National Institute for Health and Care Research, British Heart Foundation, Diabetes UK, Stroke Association, Chief Scientist Office, Loughborough University, University of Bristol, Norges Forskningsråd, Norges Idrettshøgskole, Medical Research Council, Economic and Social Research Council, World Cancer Research Fund
OpenAlex ID: W4411295690