Virulence Factors and Genes Diagnosis Treatment and Antibiotic Resistance of Staphylococcus Aureus in Ocular Infections
Year: 2025
Type: article
Abstract: Staphylococcus aureus is a major opportunistic pathogen implicated in various ocular infections. Its pathogenicity is largely due to a wide arsenal of virulence factors and antibiotic resistance genes. This study discusses the surface proteins, toxins, enzymes, adhesins, and biofilm formation contributing to its virulence. The paper also explores diagnostic approaches, current treatment options including antibiotic eye drops, and the global challenge of antimicrobial resistance. Special focus is placed on key resistance genes such as ermA, ermB, icaA, LukS, and mecA. Awareness and control of antibiotic misuse are crucial in mitigating resistance trends.
Authors: Karar Ali Abdulkhuder, Mahmood Nabeel Awad
Institution: University of Al-Qadisiyah
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411295756