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Extracutaneous primary Merkel cell carcinoma, a rare clinical entity

Year: 2025

Type: article

Abstract: ABSTRACT Merkel cell carcinoma (MCC) is a rare and aggressive primary neuroendocrine skin cancer. Extracutaneous MCC with an unknown primary skin disease is challenging and intriguing. Histologic examination coupled with a wide panel of immunohistochemical stains is mandatory to establish the diagnosis. The tumour has a high local recurrence rate, metastasis and poor prognosis. We report two such rare cases, a case of an extracutaneous primary MCC involving the breast with axillary lymph node metastasis and another case of primary extracutaneous MCC of the lymph node.

Source: Journal of diagnostic and academic pathology.

DOI: 10.4103/jdap.jdap_6_25

Authors: Menaka Ambarishan, Kirti Sharma, Mohan Narasimhamurthy

Institutions: North Tyneside General Hospital, Vanderbilt University, Vanderbilt University Medical Center

Language: English

Topic: Polyomavirus and related diseases

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4411306431

FWCI:

Cites: 9

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Related to: 10