Anesthetic management of a child with aromatic L-amino acid decarboxylase deficiency: A case report
Year: 2025
Type: article
Study design: Case Report
Abstract: This report discusses the anesthetic management of a 7-year-old child with aromatic L-amino acid decarboxylase (AADC) deficiency, a rare neurometabolic disorder. The patient underwent ventilation tube insertion and adenotonsillectomy. Similar to other adenotonsillectomy procedures, this surgery carries a higher risk of postoperative nausea and vomiting, necessitating a careful management strategy. We opted for dexamethasone as the primary antiemetic agent and limited opioid use to a single dose of fentanyl, while also incorporating dexmedetomidine for enhanced pain management alongside ketorolac and paracetamol. This case highlights the need for specialized anesthesia protocols for AADC deficiency patients to enhance safety and outcomes, particularly addressing the challenges of nausea and vomiting.
Source: Saudi Journal of Anaesthesia
Authors: Rayan Muawad, Abdullah AlDhuwaihy, Abdulrahman AlGhamdi, Ahmed Abdurazaq
Institutions: National Guard Health Affairs, King Saud University
Language: English
Subfield: Anesthesiology and Pain Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411325617