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Targeting phospholipase PLAG-15 promotes healthy aging in C. elegans via lysosomal-related genes

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Year: 2025
Type: article
Abstract: could be a promising strategy to promote healthy aging.
Source: iScience
DOI: 10.1016/j.isci.2025.112880
Authors: Sanne van der Rijt, Marte Molenaars, Rashmi Kamble, Weisha Li, Bauke V. Schomakers, Adrie D. Dane, Simone W. Denis, Michel van Weeghel, Frédéric M. Vaz, Alessandra Tammaro, Georges E. Janssens, Arwen W. Gao, Riekelt H. Houtkooper
Institutions: Amsterdam UMC Location University of Amsterdam, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam Cardiovascular Sciences
Language: English

Topic: Genetics, Aging, and Longevity in Model Organisms
Subfield: Aging
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: gold
Estimated APC paid: $3,240

Funders: Velux Stiftung, University of Minnesota, Amsterdam University Medical Centers, European Commission, Fundação de Amparo à Pesquisa do Estado de São Paulo, ZonMw, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, National Institutes of Health, Horizon 2020 Framework Programme
Awards: G1201596820, G1229162932, G2607397297, G3721864413, G3789166473, G434337789, G4759498286, G6213996172, G7724062855, G9000028377, Caenorhabditis Genetics Center
OpenAlex ID: W4411348573
FWCI: 1.018
Cites: 75
Cited by: 4
Related to: 10
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