Work

Single-leaflet reconstruction surgery for severe chronic lower limb venous insufficiency caused by post-thrombotic syndrome: a case report and literature review

Year: 2025

Type: article

Abstract: BACKGROUND: A considerable number of patients with deep vein thrombosis of the lower extremities will develop post-thrombotic syndrome even after receiving standardized anticoagulation therapy. Damage to the femoral vein valves caused by post-thrombotic syndrome can lead to severe chronic lower limb venous insufficiency and currently there is a lack of effective treatment. CASE PRESENTATION: We present a patient with pigmentation and itching due to post-thrombotic syndrome, where the anterior leaflet of the first set of valves in the superficial femoral vein was completely destroyed, while the posterior leaflet, although structurally intact, was adhered to the vessel wall. By reconstructing the posterior leaflet of the femoral vein valve and simultaneously narrowing the lumen where the anterior leaflet was located through suture ligation, we restored the valve's function to prevent venous reflux. During a 12-month follow-up period, the patient's quality of life significantly improved. CONCLUSIONS: Single-leaflet reconstruction surgery may serve as a potential treatment option for patients with post-thrombotic syndrome.

Source: Thrombosis Journal

DOI: 10.1186/s12959-025-00752-6

Authors: Dafang Liu, Hui Zhao, Jie Zhang, Liang Zhao, Yingfeng Wu

Institutions: Capital Medical University, Beijing Luhe Hospital Affiliated to Capital Medical University

Language: English

Topic: Diagnosis and Treatment of Venous Diseases

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,090