The characteristics of latent tuberculosis infection and its influencing factors in hospitalized patients in Suzhou, Jiangsu, China
Year: 2025
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: China is a country with a high burden of tuberculosis (TB). It is vital to reduce the number of new cases of TB in China. We aimed to examine and investigate the distribution and affecting factors of the latent tuberculosis infection (LTBI) detection rate in hospitalized patients in Suzhou, Jiangsu Province. METHODS: We analyzed the link between LTBI and patients' information, disease diagnosis, and blood routine indices of hospitalized patients at the Fifth People's Hospital in Suzhou from January 1, 2018, to March 31, 2024. RESULTS: Results indicated that of the 6692 patients included in the study, 39.05% of them were diagnosed with LTBI. Multivariate analysis revealed that sex, AIDS status, testing time, age, lymphocyte count, and neutrophil count were influencing factors for the detection of LTBI ( p < 0.05). However, hepatitis B, diabetes, hypertension, silicosis and monocyte count did not significantly influence LTBI detection. CONCLUSION: Sex, AIDS status, testing time, age, lymphocyte count, and neutrophil count were influencing factors for the detection of LTBI.
Source: PLoS ONE
Authors: Yanyang Zhou, Xing Lv, Shuai Zhu, Ping Xu
Institutions: Soochow University, The Fifth People’s Hospital of Suzhou
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,382
OpenAlex ID: W4411361759