Detecting the Stage of Fibrosis in Non-alcoholic Fatty Liver Disease by 9.4T Phosphorus Magnetic Resonance Spectroscopy
Year: 2025
Type: article
Study design: Observational Study
Abstract: PURPOSE: P-MRS) in differentiating advanced from mild fibrosis in non-alcoholic fatty liver disease (NAFLD) and early diagnosis at high field strength MR (9.4 Tesla). METHODS: P-MRS was performed at 9.4T MR to obtain signal peaks of different phosphorus metabolites and the changes of the ratios between the peaks were observed. RESULTS: (P < 0.01) and β-ATP/Pi (inorganic phosphate) (P < 0.05) ratio was lower in F3-4 comparing with F0. CONCLUSION: P-MRS can generally stage the liver fibrosis by comparing the ratios of the phosphorus metabolites resonance peaks at 9.4 T and more importantly it can be used for early diagnosis.
Authors: Haoxiang Li, Lin Yao, Zhongli Xiao, Shaolin Li
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411363458