Synthesis and characterization of 2,4,6-trihydroxy benzophenone and its activity as sunscreen
Year: 2025
Type: article
Abstract: Benzophenone was synthesized through a condensation reaction of benzoic acid and phloroglucinol with an Eaton reagent as a catalyst. The percentage of the product was 60%, and it was characterized using FTIR and 1H-NMR. The sunscreen activity was carried out using a UV-Vis spectrophotometer to calculate the SPF value. The synthesis result was made in several concentration variations: 100, 150, 200, 250, and 300 ppm to measure the SPF values. The results showed that the SPF values were 9.89, 13.39, 17.83, 23.77, and 28.26, respectively. Based on this, it can be concluded that these compounds have biological activity as sunscreen and samples of 200-300 ppm are included in the ultra-category as sunscreen.
Source: Acta Chimica Asiana
Authors: Emmy Yuanita, Ainni Rohmana, Maria Ulfa, Baiq Nila Sari Ningsih, Sudirman Sudirman, Ni Komang Tri Dharmayani, Ima Arum Lestarini, Maulida Septiyana, Baiq Desy Ratnasari
Language: English
Topic: Skin Protection and Aging
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411364774